Charles M. Boone

Charles Boone


  • Program Co-Director, Genetic Networks
    Codirecteur, Règne fongique : Menaces et possibilités
    Fellow, Fungal Kingdom: Threats & Opportunities
    Boursier, Réseaux Génétiques


  • University of Toronto
Department of Molecular Genetics and Donnelly Centre for Cellular and Biomolecular Research


  • Canada


PhD (Biology), McGill University
BSc (Chemistry and Math), Queen’s University


Charles Boone is a molecular biologist. He has implemented an automated form of yeast genetic analysis to cross thousands of specific strains carrying precise mutations and to map yeast genetic interactions on a large scale.

The global genetic interaction network maps a functional wiring diagram of the cell, clustering genes into specific pathways to reveal their functional connections. An understanding of the general principles of genetic networks in the yeast model system provides a framework for exploring genetic interactions in the context of human genetics.


Genetics Society of America (GSA) Edward Novitski Prize, Creativity in Genetics, 2014
Emil Christian Hansen Award for Microbiology, Carlsberg Foundation (shared with Brenda Andrews), 2013
Fellow, American Academy of Microbiology, 2012 to present
Honorary Doctorate, University of Gothenburg, 2011
Fellow of the American Association for the Advancement of Science, 2011 to present
Tier 1 Canada Research Chair in Proteomics, Bioinformatics and Functional Genomics, 2007 to present
Ira Herskowitz Award, Yeast Genetics and Molecular Biology Meeting, 2006

Relevant Publications

Costanzo, M. et al. “The genetic landscape of a cell.” Science 27, no. 5964 (2010): 425–31.


Boone Lab