Daniel Figeys

DANIEL FIGEYS

Appointment

  • Senior Fellow
  • Molecular Architecture of Life

Institution

  • University of Ottawa
Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology

Country

  • Canada

Education

PhD (Chemistry), University of Alberta
MSc (Chemistry), Université de Montréal
BSc (Chemistry), Université de Montréal

About

Daniel Figeys seeks to determine how changes in proteins, their modifications and interactions affect human health. He is also interested in using -omics based approaches to understand changes in systems, and is currently working on projects aimed at better understanding protein changes in the brain. In particular, he is studying the fundamental principle of the circadian clock, the effect of aging on the brain, and changes in models of Parkinson’s disease by proteomics. His lab is also collaborating with a microbiologist and a clinician to investigate host-microbiome interactions and their roles in inflammatory bowel disease. Figeys is also studying functional classes of proteins, including protein convertases and the SMYD family of lysine methyl transferases, and their roles in diseases. Finally, his lab is developing new technologies to study minute levels of proteins and post-translational modifications.

Awards

Canada Research Chair in Proteomics and Systems Biology
Visiting Professor for Senior International Scientists, Chinese Academy of Sciences
Ken Standing Award

Relevant Publications

Chiang, C.K. et al. "The proteomic landscape of the suprachiasmatic nucleus clock reveals large-scale coordination of key biological processes." PLoS Genet. 10 (October 2014): e1004695. https://doi.org/10.1371/journal.pgen.1004695.
Abu-Farha, M. et al. "Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2." J Mol Cell Biol. 3, no. 5 (October 2011): 301–08. https://doi.org/10.1093/jmcb/mjr025.
Lambert, J.P. et al. "Defining the budding yeast chromatin-associated interactome." Mol Syst Biol. (December 2010). https://doi.org/10.1038/msb.2010.104.
Ewing, R.W. et al. "Large-scale mapping of human protein-protein interactions by mass spectrometry." Mol Syst Biol. 3 (2007).

Connect

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