Elisabeth Binder

Bio Outline

Appointment

  • Advisor
  • Child & Brain Development

Institution

  • Max Planck Institute of Psychiatry
Translational Research in Psychiatry and Stress-Related Disorders

Country

  • Germany

Education

PhD (Neuroscience), Emory University

About

Elisabeth Binder is a medical doctor and neuroscientist.

Her main research interests are the identification of molecular moderators of the response to environmental factors, with a focus on early trauma and gene x environment interactions. She studies how such factors influence trajectories to psychiatric disease or well-being, ultimately to use this information for novel prevention and treatment strategies.

Awards

GDBBS Distinguished Alumni Award, Emory University, 2015
Max Hamilton Memorial Prize of the Collegium Internationale Neuropsychopharmacologicum (CINP), 2012
Theodore Reich Young Investigator Award of the International Society of Psychiatric Genetics, 2010
Behrens-Weise-Stiftung grant, 2009
NARSAD Michael F. Kaplan Investigator, 2007

Relevant Publications

Arloth, J. et al. "Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders." Neuron 86, no. 5 (June 2015): 1189–1202.
Zannas, A.S. et al. Genomics of Posttraumatic Stress Disorder in Posttraumatic Stress Disorder: from Neurobiology to Treatment. (Douglas Bremner Editor) John Wiley & Sons Inc. Publisher, 2015.
Mehta, D. et al. "Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder." Proc. Natl. Acad. Sci. USA 110, no. 20 (May 2013): 8302–8307.
Klengel, T. et al. "Allele-specific DNA demethylation in FKBP5: a molecular mediator of gene x childhood trauma interactions." Nat. Neurosci. 16, no. 1 (January 2013): 33–41.
Binder, E.B., and K. J. Ressler. "Emerging Methods in the Molecular Biology of Neuropsychiatric Disorders." In Handbook of Clinical Neurology, edited by Thomas E. Schlaepfer and Charles B. Nemeroff. 3rd series. Vol. Neurobiology of Psychiatric Disorders. Elsevier, 2009.
Binder, E.B. et al. "Association of FKBP5 Polymorphisms and Childhood Abuse with Risk of Posttraumatic Stress Disorder Symptoms in Adults." JAMA 299, no. 11 (2008) 1–5.
Binder, E.B., and C. B. Nemeroff. "Functional Genomics and Proteomics in Clinical Neurosciences, Implications for the Practice of Psychiatry." In Functional Genomics and Proteomics in the Clinical Neurosciences, edited by S.E. Hemby and S. Bahn. Vol. 158. Elsevier, 2006.
Binder, E.B. et al. "Polymorphisms in FKBP5 determine a novel subtype of depression characterized by increased recurrence and rapid response to antidepressant treatment." Nat. Genet. 36, no. 12 (2004): 1319–1325.