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Gerard Wright

Wright_BW

Appointment

  • Fellow
  • Fungal Kingdom: Threats & Opportunities

Institution

  • McMaster University
Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences

Country

  • Canada

Education

BSc, PhD

About

Gerry Wright is the director of the Michael G. DeGroote Institute for Infectious Disease Research and a professor in the Department of Biochemistry and Biomedical Sciences at McMaster University.

He holds the Michael G. DeGroote Chair in Infection and Anti-Infective Research and a Tier 1 Canada Research Chair in Antibiotic Biochemistry. His research is focused in the area of antimicrobial discovery, with a particular emphasis on natural products as sources of new antifungal and antibacterial agents. He is the co-founder of the Canadian Anti-Infective Innovation Network (www.cain-amr.ca). He has trained over 70 graduate students and postdocs, is the author of over 260 manuscripts and is a member of the editorial boards of several peer-reviewed journals.

Awards

Fellow of the Royal Society of Canada, 2012

Fellow American Academy of Microbiology, 2013

R.G.E. Murray Award for Career Achievement, Canadian Society of Microbiologists, 2013

NRC Research Press Senior Investigator Award, Canadian Society for Molecular Biosciences, 2016

Distinguished University Professor, McMaster University, 2016

Relevant Publications

Tyers, M. and Wright G.D. (2018) Drug combinations: A strategy to expend the life of antibiotics in the 21st Century Nature. Rev. Microbiol. 17:141-155
N. Robbins, M. Spitzer, G.D. Wright (2016) Combinatorial strategies for combating fungal infections, Virulence 8:169-185

N. Robbins, M. Spitzer, W. Wang, N. Waglechner, D.J. Patel, J.S. O’Brien, L. Ejim, O. Ejim, M. Tyers, and G.D. Wright (2016) Discovery of ibomycin, a complex macrolactone that exerts antifungal activity by impeding endocytic trafficking and membrane function Cell Chem Biol 23:1383-94
J. Wildenhain, M. Spitzer, S. Dolma, D. Bellows, N. Jarvik, R. White, M. Roy, E. Griffiths, G.D. Wright and M. Tyers (2015) Machine learning uncovers chemical synergies that surmount buffering in the genetic landscape. Cell Systems 1:383-95.

N. Robbins, M. Spitzer, T. Yu, R. P. Cerone, A, Floyd, Y.-S. Bahn, J. Heitman, D.C. Sheppard, M. Tyers, and G.D. Wright (2015) An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity Against Diverse Fungal Pathogens Cell Reports 13: 1491-92

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Wright Lab