Thomas Bosch is an evolutionary developmental biologist. His research explores the intricate interactions within metaorganisms in a simple model system, the non-senescent cnidarian Hydra.
Cnidarians represent a key transition in the evolution of animal complexity. To study them is therefore critical to our understanding of the origins of developmental mechanisms and their role in more complex organisms including humans; and also to our understanding of the impact of environmental factors, such as microbial interactions, on host performance.
Rees, T., Bosch, T., & Douglas, A.E. (2018). How the Microbiome Challenges our Concept of Self. PLoS Biology, 16(2). Doi: https://doi.org/10.1371/journal.pbio.2005358Augustin, R., Schröder, K., Murillo Rincón, A.P., Fraune, S.,…& Bosch, T. (2017). A secreted antibacterial neuropeptide shapes the microbiome in Hydra. Nature Communications, 8(1), 698. DOI: 10.1038/s41467-017-00625-1Murillo-Rincon, A.P., Klimovich, A., Pemöller, E., Taubenheim, J., Augustin, R., & Bosch, T. (2017). Spontaneous body contractions are modulated by the microbiome of Hydra. Scientific Reports, 7(1). Doi: 10.1038/s41598-017-16191-xGilbert, S.F., Bosch, T.C. & Ledón-Rettig, C. (2015). Eco-Evo-Devo: developmental symbiosis and developmental plasticity as evolutionary agents. Nature Reviews Genetics, 16(10), 611–22. DOI: https://doi.org/10.1038/nrg3982Bosch, T.C., & McFall-Ngai, M.J. (2011). Metaorganisms as the new frontier. Zoology, 114(4), 185–90. DOI: https://doi.org/10.1016/j.zool.2011.04.001