Event Information

Start Date:2018/06/04
End Date:2018/06/05
Location:Autodesk Technology Centre, MaRS Centre, Toronto

Utilizing Genetic Networks to Decode Complex Disease

The future of genetic networks is here. What methodological and conceptual approaches can we use to further decipher and attribute gene variants to complex traits? How can this knowledge be used and integrated to understand disease etiology and the longer-term pursuit of precision medicine?

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Nearly all human disease has a genetic foundation and a fundamental goal of genetics is to understand how genetic variation leads to phenotypic variation. Considerable advancements have been made in reaching this goal, yet the complexity of genetic interactions (in both coding and non-coding regions), as well as environmental determinants of complex disease makes it challenging to fully attribute genetic causality, predict predisposition, and advance whole-genome precision medicine.  A deeper understanding of how the accumulation of small genetic effects and gene interactions give rise to the overall functioning of a cell will continue to bring the broader genetics community closer to this goal.

On June 4 – 5, 2018, CIFAR’s program in Genetic Networks, in partnership with GET, will be hosting a GETx conference to explore emerging research questions and visionary ideas on gene variants and the larger genetic networks they belong within, in order to better understand complex disease. International thought leaders from research, healthcare and industry will deliberate together on how genetic interactions give rise to phenotypes, by examining this topic through various experimental designs and conceptual approaches that have the potential to drive precision medicine.

The CIFAR-GETx Conference is sponsored by the University of Toronto McLaughlin Centre and Autodesk. The conference is an affiliate event of GET, an annual forum to debate the technical, commercial, and societal impacts of advances in our ability to measure and understand people and their traits.

Please find a speaker list below and check back soon as more will be announced.



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Photo of Brenda Andrews

Brenda Andrews University of Toronto, Department of Medical Research; Terrence Donnelly Centre for Cellular & Biomolecular Research
Photo of George Church

George Church Harvard University,
Photo of Nancy J. Cox

Nancy J. Cox Vanderbilt Genetics Institute,
Photo of Marc Fiume

Marc Fiume Chief Executive Officer and Co-founder, DNAStack
Photo of Trey Ideker

Trey Ideker UCSD,
Photo of David Kelley

David Kelley Calico, Principal Data Scientist
Photo of Jennifer Listgarten

Jennifer Listgarten University of California, Berkeley
Photo of Calum MacRae

Calum MacRae Brigham and Women's Hospital, Harvard Medical School
Photo of Jason Moffat

Jason Moffat University of Toronto, Donnelly Centre for Cellular and Biomolecular Research
Photo of Jasper Rine

Jasper Rine University of California, Berkeley,
Photo of Stephen W. Scherer

Stephen W. Scherer Hospital for Sick Children, The Centre for Applied Genomics
Photo of Adam Shlien

Adam Shlien The Hospital for Sick Children ,
Photo of Gustavo A Stolovitzky

Gustavo A Stolovitzky IBM Research,
Photo of Dr. Unnur Thorsteinsdottir

Dr. Unnur Thorsteinsdottir VP, Research, DeCODE

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