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B. Brett Finlay Microbiologist

Brett Finlay‘s research explores the interaction between pathogenic bacteria, such as Salmonella and E. Coli, and their host cells. He is particularly interested by how the microbiome of humans can affect conditions such as asthma, inflammatory bowel disease, food allergies, and cardiovascular disease. He is also interested in treatment and prevention of infections, such as the C. difficile bacteria, and was the leader of the successful initiative to develop a SARS vaccine in 2003.

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Officer of Canada

Order of BC

Fellow of the Royal Society of Canada

Fellow of the Canadian Academy of Health Sciences

CIHR Distinguished Investigator

Relevant Publications

I.I. Ivanov et al, "Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine," Cell Host Microbe, vol. 4, no. 4, pp. 337-349, 2008.

I. Sekirov et al, "Gut microbiota in health and disease," Physiol. Rev., vol. 90, no. 3, pp. 859-904, 2010.

M.A. Croxen and B.B. Finlay, Molecular mechanisms of Escherichia coli pathogenicity, Nat. Rev. Microbiol., vol. 8, no. 1, pp. 26-38, 2010.

C. Lupp et al, "Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of enterobacteriaceae," Cell Host Microbe, vol. 2, no. 2, pp. 119-129, 2007.



Program Co-Director Humans & the Microbiome

Senior Fellow Humans & the Microbiome


University of British Columbia


PhD (Biochemistry) University of Alberta

BSc Honours (Biochemistry) University of Alberta



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