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B. Brett Finlay Microbiologist

Brett Finlay‘s research explores the interaction between pathogenic bacteria, such as Salmonella and E. Coli, and their host cells. He is particularly interested by how the microbiome of humans can affect conditions such as asthma, inflammatory bowel disease, food allergies, and cardiovascular disease. He is also interested in treatment and prevention of infections, such as the C. difficile bacteria, and was the leader of the successful initiative to develop a SARS vaccine in 2003.

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Awards

Officer of Canada

Order of BC

Fellow of the Royal Society of Canada

Fellow of the Canadian Academy of Health Sciences

CIHR Distinguished Investigator

Relevant Publications

I.I. Ivanov et al, "Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine," Cell Host Microbe, vol. 4, no. 4, pp. 337-349, 2008.

I. Sekirov et al, "Gut microbiota in health and disease," Physiol. Rev., vol. 90, no. 3, pp. 859-904, 2010.

M.A. Croxen and B.B. Finlay, Molecular mechanisms of Escherichia coli pathogenicity, Nat. Rev. Microbiol., vol. 8, no. 1, pp. 26-38, 2010.

C. Lupp et al, "Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of enterobacteriaceae," Cell Host Microbe, vol. 2, no. 2, pp. 119-129, 2007.

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Appointments

Program Co-Director Humans & the Microbiome

Senior Fellow Humans & the Microbiome

Institution

University of British Columbia

Education

PhD (Biochemistry) University of Alberta

BSc Honours (Biochemistry) University of Alberta

Country

Canada

Ideas Related to B. Brett Finlay

Symposium Debrief | Humans & the Microbiome

Symposium Brief – The Microbiome in Human Health London

Roundtable Objectives  By bringing together researchers across different areas of expertise, including microbiology and anthropology, CIFAR’s Humans & The Microbiome...

Reach Magazine | Humans & the Microbiome

Our Microbes, Ourselves

CIFAR’s Humans & the Microbiome program is untangling how the life that lives in and on us affects our health,...

News | Humans & the Microbiome

Yeast found in the gut linked to asthma

Yeast has joined the list of gut microbes that play a role in driving diseases like asthma. In a study...

News | Humans & the Microbiome

Q & A: Let Them Eat Dirt

Improvements in hygiene and the development of antibiotics made huge improvements in health over the 20th century. But B. Brett...

News | Video | Humans & the Microbiome

Robogut: a new generation of sequencing

CIFAR Senior Fellow & Program Director Brett Finlay presents on the human microbiome at a Public Salon event organized by...

Announcement

CIFAR revs up collaborations in four new programs

CIFAR’s four new programs are having their first collaborative meetings, delving into questions such as how to improve solar energy, define the complexities of human consciousness, and improve health through a better understanding of microbes and the molecular basis of life.