Go Back

Photo of Brian Dias

Brian Dias

Research in the Dias Laboratory seeks to understand how the nervous system is impacted by stress or trauma, and how parental legacies of stress or trauma influence offspring by leaving imprints on the parental germline (sperm and egg). Armed with this understanding, Dr. Dias and his team aim to devise therapeutic interventions to ameliorate the effects of stress or trauma in both parental populations and their offspring. To investigate how the biology of an organism and its responsiveness to stress or trauma is influenced by micro- (genome, epigenome and hormones), and macro-environments (ancestral, in utero and post-natal experiences), the Dias Laboratory uses molecular, cellular, genetic, epigenetic, physiological, and behavioral approaches. While most of Dr. Dias’ work uses mice, generous collaborators have enabled Dr. Dias and his team to begin investigating the biological basis of behavioral states and neuropsychiatric disorders, in non-human primates, and humans, in multi-generational contexts. 

Awards

Reves Center Distinguished Lecturer in International Studies

Emory University Research Council Award

Participant at 2016 Sci-Foo Camp, 2016.

FAPESP-SPRINT Award

Consciousness – Perspectives from Western Neuroscience and Buddhist Philosophy” – A conversation with The Dalai Lama and Dr. Christof Koch (Director, Allen Brain Institute), 2016.

Relevant Publications

B.G. Dias and K.J. Ressler, "Parental olfactory experience influences behavior and neural structure in subsequent generations," Nature Neuroscience 17(1): 89-96. PMID: 24292232; PMCID: PMC3923835, 2014.

B.G. Dias and K.J. Ressler, "Experimental evidence needed to demonstrate inter- and trans-generational effects of ancestral experiences in mammals," Bioessays 36: 919-923. PMID: 25154497; PMCID: PMC4293024, 2014.

B.G. Dias, J.V. Goodman, R. Ahluwalia, A.E. Easton, R. Andero, K.J. Ressler, "Amygdala-dependent fear memory consolidation via miR-34a and Notch signaling," Neuron 83(4): 906-918. PMID: 25123309; PMCID: PMC4172484, 2014.

B.G. Dias, S.B. Banerjee, J.V. Goodman, K.J. Ressler, "Towards new approaches to disorders of anxiety and fear," Current Opinion Neurobiol 23(3): 346-352. PMID: 23402950; PMCID: PMC3672317, 2013.

A. Nair, K.C. Vadodaria, S.B. Banerjee, M. Benekaredd, B.G. Dias, R.S. Duman, V.A. Vaidya, "Stressor-specific regulation of Brain Derived Neurotrophic Factor transcripts and cyclic AMP response element binding protein expression in the postnatal and adult rat hippocampus," Neuropsychopharmacology 32(7): 1504-1519. PMID: 17164818, 2007.

Connect

Appointment

CIFAR Azrieli Global Scholar Child & Brain Development

Institution

Emory UniversityDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Yerkes National Primate Research Center

Education

PhD. (Neuroscience) University of Texas at Austin

MSc. (Molecular Biology) Tata Institute of Fundamental Research

BSc. (Life Sciences/Biochemistry) St Xavier’s College

Country

United States

No Assets Found

Sorry, we did not find any assets matching these filters.