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Charles M. Boone Molecular biologist

Charles Boone has implemented an automated form of yeast genetic analysis to cross thousands of specific strains carrying precise mutations and to map yeast genetic interactions on a large scale. The global genetic interaction network maps a functional wiring diagram of the cell, clustering genes into specific pathways to reveal their functional connections. An understanding of the general principles of genetic networks in the yeast model system provides a framework for exploring genetic interactions in the context of human genetics.


Genetics Society of America (GSA) Edward Novitski Prize, Creativity in genetics, 2014.

Emil Christian Hansen Award for Microbiology, Carlsburg Foundation (with Brenda Andrews), 2013.

Fellow, American Academy of Microbiology, 2012-present.

Honorary Doctorate Degree, University of Gothenburg, 2011.

Fellow of the American Association for the Advancement of Science, 2011-present.

Canada Research Chair (tier 1), Proteomics, Bioinformatics and Functional Genomics, 2007-present.

Ira Herskowitz Award, Yeast Genetics and Molecular Biology Meeting, 2006.

Relevant Publications

M. Costanzo et al., "The genetic landscape of a cell," Science, 27, 5964 (2010): 425-431, doi: 10.1126/science.1180823.



Program Co-Director Genetic Networks


University of TorontoDonnelly Centre for Cellular & Biomolecular Research- Department of Molecular Genetics


PhD (Biology) McGill University

B.Sc. (Chemistry and Math) Queens University



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