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Elisabeth Binder Medical Doctor and Neuroscientist

Elisabeth Binder’s main research interests are the identification of molecular moderators of the response to environmental factors, with a focus on early trauma and gene x environment interactions. She studies how such factors influence trajectories to psychiatric disease or well-being to ultimately use this information for novel prevention and treatment strategies.

Awards

GDBBS Distinguished Alumni Award, Emory University, 2015.

Max Hamilton Memorial Prize of the Collegium Internationale Neuropsychopharmacologicum (CINP), 2012.

Theodore Reich Young Investigator Award of the International Society of Psychiatric Genetics, 2010.

Behrens-Weise-Stiftung grant, 2009.

NARSAD Michael F. Kaplan Investigator, 2007.

Relevant Publications

E.B. Binder et al, "Polymorphisms in FKBP5 determine a novel subtype of depression characterized by increased recurrence and rapid response to antidepressant treatment," Nat. Genet., vol. 36, no. 12, pp. 1319-25, 2004.

E.B. Binder et al, "Association of FKBP5 Polymorphisms and Childhood Abuse with Risk of Posttraumatic Stress Disorder Symptoms in Adults," JAMA, vol. 299, no. 11, pp. 1-5, 2008.

T. Klengel et al, "Allele-specific DNA demethylation in FKBP5: a molecular mediator of gene x childhood trauma interactions," Nat. Neurosci., vol. 16, no. 1, pp. 33-41, Jan. 2013.

J. Arloth et al, "Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC. Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders," Neuron, vol. 86, no. 5, pp. 1189-202, Jun. 2015.

D. Mehta et al, "Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder," Proc. Natl. Acad. Sci. USA, vol. 110, no. 20, pp. 8302-7, May 2013.

Books

E. B. Binder and K. J. Ressler, "Emerging Methods in the Molecular Biology of Neuropsychiatric Disorders," in Handbook of Clinical Neurology 3rd Series Volume ‘Neurobiology of Psychiatric Disorders’ (Thomas E. Schlaepfer & Charles B. Nemeroff, Eds,) 2009.

E. B. Binder and C. B. Nemeroff, "Functional Genomics and Proteomics in Clinical Neurosciences, Implications for the Practice of Psychiatry," In: Functional Genomics and Proteomics in Clinical Neurosciences. (S.E. Hemby and S. Bahn Eds.) 2006.

A. S. Zannas et al, Genomics of Posttraumatic Stress Disorder in Posttraumatic Stress Disorder: from Neurobiology to Treatment. (Douglas Bremner Editor) John Wiley & Sons Inc. Publisher, 2015.

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Appointment

Advisor Child & Brain Development

Institution

Max Planck Institute of PsychiatryDepartment of Translational Research in Psychiatry and Stress-related Disorders

Education

PhD (Neuroscience) Emory University

Country

Germany

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