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Eric A. Shoubridge Molecular Neurogeneticist

Eric Shoubridge’s laboratory focuses on the molecular genetics and cell biology of mitochondrial encephelomyopathies, diseases that result from deficiencies in the mitochondrial respiratory chain. His lab is also developing systems to transform mammalian mitochondria to create models of the human diseases. Shoubridge is using primary patient cell cultures and animal models to investigate the molecular mechanisms underlying these diseases and to identify new nuclear gene defects.


Elected Fellow of the Royal Society of Canada, 2004.

Relevant Publications

Z. Zhu et al, "SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome," Nat. Genet., vol. 20, no. 4, pp. 337-343, Dec. 1998.



Senior Fellow Genetic Networks


McGill UniversityDepartments of Neurology and Neurosurgery, and Human Genetics at the Montreal Neurological Institute


PhD (Zoology) University of British Columbia

MSc (Ecology) McGill University

BSc (Marine Science and Ecology) McGill University



Ideas Related to Eric A. Shoubridge

News | Genetic Networks

Glitch in gene leads to clues in human disease

A team of researchers led by Fellow Eric Shoubridge (McGill) in CIFAR’s Genetic Networks program discovered a new genetic defect...

News | Genetic Networks

Research team identifies human disease gene with the help of fruit flies

CIFAR Fellow Eric A. Shoubridge with his colleagues at McGill University collaborated with researchers at Baylor College of Medicine in Houston...