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Maitreya Dunham Geneticist

Maitreya Dunham’s lab studies genome evolution in yeasts from a novel genomics perspective. To this end, her lab uses experimental evolution and comparative genomics to investigate how genomes evolve on timecourses from a few weeks to millions of years. One important path for evolution is via gene and chromosome copy number change. Several projects in the lab aim to identify the causes and consequences of copy number changes in cells adapting to new environments. The lab is also currently working on a variety of related technology development projects, ranging from instrument engineering for parallelized strain cultivation to applications of next generation sequencing in genome characterization.


Basil O’Connor Scholar, March of Dimes, 2011.

Rita Allen Foundation Scholar, 2010.

Marian E. Smith Junior Faculty Award, 2009.

Relevant Publications

Sunshine et al, "The fitness consequences of aneuploidy are driven by condition-dependent gene effects," PloS Biol., vol. 13, no. 5, pp. e1002155, May 2015.

E.A. Hope and M.J. Dunham, "Ploidy-regulated variation in biofilm-related phenotypes in natural isolates of Saccharomyces cerevisiae," G3., vol. 4, no. 9, pp. 1773-86, 2014.

I. Liachko et al, "GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris," PLoS Genet., vol. 10, no. 3, pp. 399-409, Mar. 2014.

C. Payan et al, "The Dynamics of Diverse Segmental Amplifications in Populations of Saccharomyces cerevisiae Adapting to Strong Selection," G3., vol. 4, no. 3, pp. 399-409, Mar. 2014.

A.A. Caudy et al, "A New System for Comparative Functional Genomics of Saccharomyces Yeasts," Genetics, vol. 195, no. 1, pp. 275-87, Sept. 2013.


M.J. Dunham et al, Methods in Yeast Genetics and Genomics, 2015 Edition: A CSHL Course Manual. Cold Spring Harbor Laboratory Press, 2015.



Senior Fellow Genetic Networks


University of WashingtonDepartment of Genome Sciences


Lewis-Sigler Fellow Princeton University

PhD (Genetics) Stanford University

B.S. (Biology) Massachusetts Institute of Technology


United States

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CIFAR announces new research appointments to research programs

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