Martin Blaser is interested in understanding the relationships we have with our persistently colonizing bacteria. His work over the past 30 years focused on human pathogens, including Campylobacter species and Helicobacter pylori, which also are model systems for understanding interactions of residential bacteria with their human hosts. Over the last decade, he has been actively studying the relationship of the human microbiome with humans in terms of evolution, persistence mechanisms, host-interactions, and population dynamics. He has been studying extinctions of ancient microbiota constituents, This in turn concerns health and such important diseases as asthma, obesity, diabetes and allergies.
Alexander Fleming Award, 2014.
Infectious Diseases Society of America Oswald Avery Award, 1992.
A. Nomura et al, "Helicobacter pylori infection and gastric carcinoma in a population of Japanese-Americans in Hawaii," New England Journal of Medicine, vol. 325, pp. 1132-1136, 1991.
M. J. Blaser and D. Kirschner, "Dynamics of Helicobacter pylori colonization in relation to the host response," Proceedings of the National Academy of Sciences, USA, vol. 96, pp. 8359-8364, 1999.
C. Ghose et al, "East Asian genotypes of Helicobacter pylori: strains in Amerindians provide evidence for its ancient human carriage," Proceedings of the National Academy of Science, USA, vol. 99, pp. 15107-15111, 2002.
I. Cho et al, "Antibiotics in early life alter the murine colonic microbiome and adiposity," Nature, vol. 488, pp. 621-626, 2012.
L. M. Cox et al, "Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences," Cell, vol. 158, pp. 705-721, 2014.
MJ Blaser. Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues, New York: Henry Holt and Co, 2014.
J Bennett, R Dolin and MJ Blaser (Editors). Principles and Practice of Infectious Diseases, 8th edition. Philadelphia, PA: Elsevier, 2014.
MJ Blaser, PD Smith, JI Ravdin, H Greenberg and RL Guerrant (Editors). Infections of the Gastrointestinal Tract, 2nd edition. Philadelphia PA: Lippincott, Williams & Wilkins, 2014.
Advisor Humans & the Microbiome
New York UniversityDepartment of Medicine; Department of Microbiology
MD New York University
BA (Economics) University of Pennsylvania
Ideas Related to Martin Blaser
Exposure to antibiotics disrupts the balance of bacterial communities in the gut microbiome and may spur the onset of type-1...